Vitiligo is a condition in which skin loses melanin, the pigment that determines the color of skin, hair and eyes. Symptoms include premature whitening or graying of the hair on scalp, eyelashes, eyebrows or beard, loss of color in the tissues that line the inside of mouth and loss of or change in color of the inner layer of eye. Treatment includes corticosteroid therapy, immunomodulatory and surgery. 

Causes: The exact causes of vitiligo are unclear. A number of factors may contribute.

These include an autoimmune disorder, in which the immune system becomes overactive and destroys the melanocytes a genetic oxidative stress imbalance, a stressful event , harm to the skin due to a critical sunburn or cut , exposure to some chemicals, a neural cause, heredity, as it may run in families, a virus… 

Vitiligo is not contagious. One person cannot catch it from another. 

It can appear at any age, but studies suggest that it is more likely to start around the age of 20 years Vitiligo is an orphan disease


The entire dermatology range is available in its cosmetic formulation.



Psoriasis is a chronic inflammatory skin disease primarily causing scaling and inflammation of skin, but it can also result in systemic inflammation and adverse consequences for a patient's overall health. 

It is characterized by sharply demarcated, scaly, red skin lesions most often on the elbows, knees, scalps, hands and feet. It occurs when the body’s immune system sends out faulty signals that speed up the growth cycle of skin cells. Plaques appear in cycles known as flares, and can be triggered by the bacterial or the viral infections, stress, medication and smoking. It is an autoimmune disease.

Psoriasis is considered to be one of the most prevalent autoimmune diseases caused by the inappropriate activation of the cellular immune system, triggering the new skin cells to generate at an alarming rate. Scientists have been unable to find out the exact causes of the psoriasis.

MEGA BioPharma R&D works allowed to show and confirm several of the amazing properties of BIONACRE, in particular its capacity to repair several types of tissues (bone, soft tissues) and place itself under the local systemic regulation of the receiver site, as if it was “biomimetic:


The entire dermatology range is available in its cosmetic formulation.

HIGHEST Safety for a HIGHER Performance


Based on literature review, the NACRE by itself does not raise toxicological concerns.

In order to demonstrate the full BIOCOMPATIBILITY of BIONACRE, BIOLOGICAL studies are conducted by product, according to the regulatory requirements, e.g; ISO 10993-serie such as cytotoxicity, genotoxicity, acute systemic toxicity, hemocompatibility, etc...


QUALITY CONTROLis applied during the whole process chain:

Since controlled sourcing shell selection, bases on detailed specifications

In each step of the manufacturing process

Until the final production and packaging of the devices (including Gamma sterilization)


SPECIFIC PATENTED TREATMENTS are applied in order to boost some physical properties and reinforce the natural efficacy of the biomaterial

Mega Bio Pharma®